MK-677 is a Active Growth Hormone Secretagogue. AGHS are used by professional athletes, bodybuilders as an alternative to steroids or other artificial substances. This product does not come with a long list of side effects, which makes it a lot more appealing.
How Does MK-677 Work?
According to the US National Center for Biotechnology Information study – MK677 works by stimulating Growth Hormone (GH) secretion in adults. And even though increased GH secretion doesn’t necessarily mean bigger muscles, this hormone showed a statistically significant increase in muscle strength in lower and upper body parts. Also, that same study showed, that MK-677 had a significant effect in increasing Fat-Free Mass (FFM) over 12 months of the administration. So, it’s safe to conclude that MK-677 works by stimulating your body to produce the hormones needed to build bigger muscles and increase FFM.
You may have read lots of MK-677 reviews. And while it’s great to stay informed on the topic and gather a lot of information the downside is that most of the MK-677 reviews available on the internet come with no scientific back-up whatsoever.
We’ve put together a list of benefits that also come with the confirmation of experts through trials and tests.
As highlighted in the NCBI study regarding the effects of MK 677 effects on body fat, it showed a significant increase in FFM in 12 months of the administration. To quote the results of this study: “MK-677 enhanced pulsatile GH secretion and significantly increased FFM over 12 months and was generally well tolerated.”. So, you will no longer have to believe random MK 677 reviews for its benefits when it comes to reducing body fat. The study mentioned above clearly shows that over 12 months of administering MK-677. This statement is also backed up by the conclusion of another study that used MK-677 (also referred to as Nutrobal) for a two-month treatment of obese subjects. It provided very promising results.
You’ve probably seen in other MK-677 reviews that this supplement has great effects when it comes to increasing muscle mass. Well, it’s true that Nutrobal MK-677 helps with increasing muscle mass, as shown in the table of the NCBI study on the effects of MK-677 over Body Composition. While the immediate effect of MK-677 isn’t considerable, the values are higher compared to the baseline ones and the Placebo group.
Besides doing great work when it comes to reducing body fat and increasing muscle mass, one of the best MK-677 benefits came as a surprise for researchers. One study showed that prolonged oral treatment with MK-677 considerably improves sleep quality.
Expectations and Results of Ibutamoren
By summing up the scientifically-proven benefits of using MK-677 we can also take a good look at how this supplement lives up to its expectations. Most people use MK-677 bodybuilding supplements for their effects on muscle mass and body fat. When it comes to increasing muscle mass, the results indicated a growth, but the rate isn’t exceptional as most users probably expect. Don’t forget that Ibutamoren doesn’t just create muscle out of thin air. You need to follow a steady and sustained workout routine in order to get the muscles you want.
Also, most people reading MK-677 reviews expect that the supplement will help them lose fat faster. In-depth studies also confirm that and together with a good training routine, your body fat index will drop.
How Does MK-677 Perform in Scientific Facts?
Numerous tests and trials have been performed to reach a conclusion about the efficiency of Nutrobal MK-677. As seen before, this supplement has positive effects when it comes to secreting Growth Hormone, building muscle mass, and reducing body fat.
What you won’t find in most other MK-677 reviews is that it was put to the test to see if it makes any difference in Alzheimer Disease patients. According to a study posted in Neurology, the results indicate no clinical effect on the progression of Alzheimer when MK-677 was administrated.
Also, if you were wondering whether MK-677 is legal, you should know that in the United States, this supplement is still an Investigational New Drug. This means that it didn’t get the green light for mass-marketing and consumption. The Australian authorities deemed Ibutamoren a Schedule 4 medicine, which means it can be used only with a prescription. It’s illegal for supplement stores to sell it.
MK-677 Side Effects
We couldn’t call this a complete MK-677 review without also mentioning the side effects. We’re all about giving you full information about this supplement, so here are the most common side effects you should expect when taking MK-677.
According to the NCBI study for the Effect of MK-677 on Body Composition and Clinical Outcomes in Healthy Older Adults, the supplement leads to a significant increase in body water. 1.7 kg was the increase when MK-677 was administered, while intracellular water also increased with 0.8 kg.
Another common side effect of administering MK-677 is an increased feeling of hunger. To cite the study conducted on older adults: “The most frequent side effects were an increase in appetite that subsided within a few months and transient, mild lower extremity edema and muscle pain.”
- Insulin Insensitivity (rare)
A less-frequent side effect that is usually not often mentioned in other MK-677 reviews is reduced insulin sensitivity. There are no records among bodybuilders or active athletes, though. Just there is the study conducted by the NCBI on older adults that registered a low increase of insulin sensitivity (P<0.001).
Even though this supplement is not available for purchase just yet, and using it is solely your responsibility, we thought it’s better to have a fact-checked guideline when it comes to dosage. So, check out the recommended dosage for different purposes, as shown by the studies conducted by scientists.
Unlike other MK-677 reviews, we’re backing these up with scientific data:
- Developing lean muscles – the recommended dosage, that showed the best results when talking about increasing muscle mass, is 25 mg per day. “ A starting dose of 25 mg by mouth daily for Ibutamoren is recommended given that this is the dose studied in randomized controlled trials” – as recommended in the NCBI study on “The Safety and Efficacy of Growth Hormone Secretagogues”.
- Fat loss – if your main goal is to burn fat faster, you should consider lowering the dosage of MK-677 since it was proven that 25 mg per day also increases water retention. You don’t want to replace fat with water so a 15 to 20 mg/day dose should be enough. This data is confirmed by the two-month treatment of obese subjects with MK-677. Even though the starting dose was 25 mg, this was dropped for some test subjects, and it had better results.
Can Females Take MK-677?
Of course! The vast majority of studies using MK-677 were conducted on men and women equally. Even more, there’s a study looking into the effects of MK-677 on bone development and density in Postmenopausal Osteoporotic Women, so there’s no reason why women shouldn’t use this supplement.
Can You Drink Alcohol on Nutrobal?
While there’s no study clearly stating the negative effects of alcohol consumption during MK-677 administration, all the studies, such as this one, excluded subjects that consumed alcohol regularly.
Is Post Cycle Therapy Required After MK-677?
Since the studies using a dose of 25 mg of MK-677 on elderly adults were conducted over 2 years without any PCT involved, we can safely conclude that this supplement does not need a Post Cycle Therapy of its own.
Verdict and Our Recommendation for 2020
And that sums up our research. Our goal was to provide one of the best MK-677 reviews in 2020. We went through dozens of clinical trials and scientific data to get the best answers to your questions and give you a detailed set of information regarding MK-677.
After everything, we’ve learned, there’s no doubt that this supplement is one of the best SARMs for cutting body fat, increasing muscle mass, and improving appetite. All those benefits come with reduced side effects, and that’s what makes MK-677 superior compared to steroids and other supplements out there.